VeraBIND Borrelia Antibody Assay

Advanced Detection of Borrelia burgdorferi Antibodies for Research

The VeraBIND™ Borrelia Antibody Assay (RUO) is a state-of-the-art, bead-based fluorescent immunoassay designed for the multiplex detection of total IgG, IgM, and IgA antibodies against Borrelia burgdorferi in serum, plasma, saliva, or saline oral rinse samples. This semi-automated assay provides precise detection and quantification, making it an essential tool for researchers studying Lyme disease and related immunological responses. 

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Key Features:

  • Multiplex Detection:
    Simultaneously detects total IgG, IgM, and IgA antibodies against Borrelia burgdorferi, offering comprehensive insights into immune responses.

  • Advanced Interference Removal:
    Utilizes proprietary VeraBIND™ Clean Beads to efficiently remove a wide range of endogenous human immunoglobulin interferences, ensuring cleaner samples and more accurate results.

  • Quantitative Analysis:
    The optional VeraBIND Triplex Antibody Calibrator Set enables the precise quantification of IgG, IgM, and IgA antibodies, enhancing the depth and reliability of your research. 

  • High Sensitivity and Specificity:
    Demonstrated to deliver 100% sensitivity and specificity for detecting Borrelia burgdorferi antibodies, ensuring the highest level of accuracy in your studies.

How It Works

  1. Sample Cleaning:
    Serum, plasma, saliva, or saline oral rinse samples are treated with VeraBIND Clean Beads to remove non-specific immunoglobulins and other interferences.

  2. Antibody Capture:
    The cleaned samples are incubated with Borrelia antigen-coated VeraBIND Capture Beads, which specifically capture antibodies against Borrelia burgdorferi.

  3. Detection and Measurement:
    After washing, the captured antibodies are detected using a triplex fluorescent conjugate. The results can be quantified using the optional Triplex Antibody Calibrator Set.

Applications

  • Lyme Disease Research:
    Provides valuable data for studying the presence and persistence of antibodies following Borrelia burgdorferi infection.

  • Immunology Studies:
    Ideal for research into the immune responses associated with Lyme disease and other tick-borne illnesses.

  • Assay Development:
    Supports the development of new, highly sensitive assays for detecting antibodies against Borrelia burgdorferi.

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Kit Includes

  • VeraBIND Clean Beads 

  • 25X Wash Buffer 

  • Phosphate Buffer Saline 

  • Triplex Conjugate 

  • Elution Buffer 

  • Neutralization Buffer 

  • Borrelia Antigen-Coated VeraBIND Capture Beads 

Materials Required But Not Provided

  • BioPlex 2200 Lyme Total Control Set 

  • Vortex mixer

  • Laboratory rocker

  • Multi-channel pipettes

  • Well plates

  • Plate magnets

  • Fluorescent reader. 

  • Optional: VeraBIND Triplex Antibody Calibrator Set (Part Number 400092) 

Ordering Information

  • Product Name: VeraBIND™ Borrelia Antibody Assay

  • Catalog Number: 500082

Regulatory Status

For Research Use Only. Not for use in diagnostic procedures.